Endocrine Abstracts

Introduction: Follicular tumours of the thyroid gland include benign follicular adenomas, follicular carcinomas and the follicular variant of papillary carcinoma. Although, molecular markers are a promising area of research to differentiate thyroid neoplasms, there is ample room for improvement in the research and clinical applications in this field. Furthermore, the final diagnosis requires thyroid lobectomy. The present study examined whether a differential protein expressio...

Introduction: MicroRNAs (miRNAs) are short non-coding RNAs that regulate translation or degradation of target mRNAs. Therefore, miRNAs control gene expression in many biological processes, including proliferation, apoptosis, and differentiation. Deregulation of miRNAs expression is an important contributor to tumour development and progression. Even though several genetic and epigenetic lesions have been identified in human thyroid cancer, particularly in the papillary histoty...